A Comparative Study of Intramuscular Ketamine and a Combination of Intramuscular Dexmedetomidine and Ketamine as Premedication in Paediatric Anesthesia

Introduction: Preoperative anxiety is an issue of concern in paediatric anaesthesia practice. Forceful transfer children into the operating room can cause long-term psychological trauma. This clinical study compares intramuscular ketamine and a combination dexmedetomidine as anaesthetic premedicants terms +anxiolysis, sedation ease IV cannulation.
 Objectives: To compare level preoperative anxiety, cannulation following premedication between ketamine.
 Methods: Total 60 patients belonging to American Society Anaesthesiologists physical status I-II, age group two ten years, scheduled for elective surgery under general were included study; Group A received 3mg/kg body weight while B 2mg/kg 1mcg/kg intramuscular. The outcome variables score (Richmond Agitation Sedation Scale), cannula acceptance (IV Acceptance Score), parental separation (Separation Score).
 Results: groups comparable patient characteristics hemodynamic parameters groups. Median (IQR) at 10 min -1 (-2—0) 0(-1—1) (p< 0.001); mean scores 3.76± 0.43 3.36±0.55 3.73±0.44 4.53±7.27 (p= 0.001) respectively.
 Conclusion: Combination superior alone 15 but anxiolysis.